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Biomedical Applications

We are interested in the transport phenomena applications of biomedical processes. We have worked closely with medical professionals to develop engineering insight into biomedical processes for the purpose of optimizing treatment planning and drug delivery, through the use of physics-based models. We had been active in two joint projects, one involving modeling of airflow in the upper airway of an exercising horse (with Professor Normand Ducharme of the College of Veterinary Medicine, Cornell University) and the other involving modeling of radioactivity delivery to a melanoma tumor during radioimmunotherapy (with Professor Ekaterina Dadachova of the Albert Einstein College of Medicine).

Selected Publications

  • Rakesh, V., A. D. Schweitzer, O. Zaragoza, R. Bryan, K. Wong, A. K. Datta, A. Casadevall and E. Dadachova. 2008. Finite element model of interaction between fungal polysaccharide and monoclonal antibody in the capsule of Cryptococcus neoformans. J. Physical Chemistry, Part B, 112:8514-8522.
  • Rakesh, V., N.G. Ducharme, J. Cheetham, A. K. Datta, and A. P. Pease. 2008. Implications of different degrees of arytenoid cartilage adduction on equine upper airway characteristics. Equine Veterinary Journal, 40(7):629-635.
  • Rakesh, V., N.G. Ducharme, A.K. Datta, J. Cheetham and A.P. Pease. 2008. Development of equine upper airway fluid mechanics model for thoroughbred racehorses. Equine Veterinary Journal, 40(3):272-279.
  • Rakesh, V., A. K. Datta, N. G. Ducharme and A. P. Pease. 2008. Simulation of turbulent airflow using a CT based upper airway model of a racehorse. Journal of Biomechanical Engineering, Transactions of the American Society of Mechanical Engineers, 130(3):031011.
  • Datta, A. K. 2008. Status of physics-based models in the design of food products, processes and equipment. Critical Reviews in Food Science and Food Safety, 7(1):114-116.
  • Schweitzer, A.D., V. Rakesh, E. Revskaya, A.K. Datta, A. Casadevall, and E. Dadachova. 2007. Computational model predicts effective delivery of 188-Re-labeled melanin-binding antibody to the metastatic melanoma tumors with wide range of melanin concentrations, Melanoma Research, 17(5), 291-303.

Ashim K. Datta

Ashim K. Datta

  • Professor
    Biological & Environmental Engineering
    Cornell University
    208 Riley-Robb Hall
    Ithaca, NY 14853-5701
  • Tel: (607) 255-2482
  • Fax: (607) 255-4080